Global conflicts, health risks, populist political movements and changing attitudes toward trade all represent unpredictable influences on global economic stability, which has significant impact on states’ economies. In 2016, the world saw a number of political and trade issues—such as the United Kingdom’s decision to exit the European Union, also known as Brexit, and Americans’ resistance to international trade agreements—emerge unexpectedly that will continue to resonate in 2017. With little certainty as to how these and other issues will play out, global economic instability will be the most important international issue facing states this year.