Three out of every four dollars spent for health care is spent on chronic diseases. For state budgets, the drain is even greater—Medicaid spends 83 cents of every dollar on chronic diseases. This CSG Health Policy Academy focused on chronic diseases, their burden to society and evidence-based strategies for prevention, identification and treatment. Whether it is heart disease, mental health, diabetes, Alzheimer’s disease or Hepatitis C, considerable research suggests we can do better for those with these often devastating diseases while also being better stewards of state budgets. State policy strategies were presented to meet the dual goals of improving health outcomes and reducing health care spending.